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What is the most important information I should know about Accutane?
• Accutane is a medication taken to treat severe nodular acne that hasnot been helped by other treatments, including antibiotics brandis accutane journal. However, Accutanecan cause serious side effects brandis accutane journal. Before starting treatment with Accutane, discusswith your doctor how bad the acne is, the possible benefits of Accutane, andthe possible side effects brandis accutane journal. Your doctor will ask you to read and sign a formindicating that you understand the serious risks associated with Accutane therapy brandis accutane journal.
• Do not take Accutane if you are pregnant or if you could become pregnantduring treatment or for one month after you stop taking Accutane brandis accutane journal. Accutane isin the FDA pregnancy category X brandis accutane journal. This means that Accutane is known to causesevere birth defects in an unborn baby brandis accutane journal. It can also cause miscarriage, prematurebirth, or death of the baby brandis accutane journal. You must take a pregnancy test and have negativeresults when you and your doctor decide that Accutane may be beneficial foryour condition brandis accutane journal. You must have a second pregnancy test with negative resultsduring the first 5 days of the menstrual period right before you start takingAccutane brandis accutane journal. Two reliable forms of birth control must be used at the same time(unless abstinence is the chosen method of birth control or if you have undergonea hysterectomy) for one month before starting treatment with Accutane, duringtreatment with Accutane, and for at least 1 month following the end of treatment brandis accutane journal. You will also be asked to take a pregnancy test on a monthly basis brandis accutane journal. Your doctorwill discuss with you and provide for you a video and written information regardingchoices for birth control, possible causes for birth control failure, and theimportance of using birth control while taking Accutane brandis accutane journal. If you become pregnant,stop using birth control, or miss your menstrual period, immediately stop takingAccutane and notify your doctor brandis accutane journal.
• Some patients have experienced depression (including feelings of sadness,irritability, unusual tiredness, trouble concentrating, and loss of appetite)and suicidal thoughts and/or behavior during, and soon after stopping, treatmentwith Accutane brandis accutane journal. Notify your doctor immediately if you begin to experience signsof depression or if you begin to have thoughts about taking your own life duringor shortly following treatment with Accutane brandis accutane journal.
• Do not take vitamin supplements containing vitamin A during treatmentwith Accutane brandis accutane journal. This could cause increased side effects brandis accutane journal.
• Do not donate blood while taking Accutane and for at least 1 month followingthe end of treatment brandis accutane journal. Blood donated while taking Accutane may be given to apregnant woman and be harmful to her baby brandis accutane journal.
• Do not use wax hair removal systems or have any skin resurfacing procedures(such as dermabrasion or laser treatment) performed while taking Accutane andfor six months following treatment due to the possibility of scarring brandis accutane journal.
• Avoid exposure to sunlight or UV rays while taking Accutane brandis accutane journal. Accutanemay increase the sensitivity of the skin to sunlight and a severe sunburn couldresult brandis accutane journal.
• Use caution when driving a vehicle at night brandis accutane journal. Accutane can cause decreasednight vision brandis accutane journal. The onset of decreased night vision may be sudden brandis accutane journal.
• Take all of the Accutane that has been prescribed for you even if yoursymptoms start to improve brandis accutane journal. The acne may seem to get worse at the start of therapy,but should then begin to improve brandis accutane journal. For the best results, finish all of the medicationthat has been prescribed brandis accutane journal. You may require more than one course of therapy withAccutane brandis accutane journal.


What is Accutane?
• Accutane is a form of vitamin A brandis accutane journal. It decreases the amount of sebum (oil)that is released by the sebaceous (oil) glands, and it increases that rate atwhich the skin renews itself brandis accutane journal.
• Accutane is used to treat severe nodular acne that has not respondedto other treatments, including antibiotics brandis accutane journal.
• Accutane may also be used for purposes other than those listed in thismedication guide brandis accutane journal.


What should I discuss with my healthcare provider before taking Accutane?
• Before taking Accutane, tell your doctor if you have
· a personal or family history of mental problems including depression,suicidal behavior, or psychosis (loss of contact with reality, hearing voices,or seeing things that are not there);
· diabetes;
· asthma;
· heart disease;
· osteoporosis (bone loss) or weak bones;
· anorexia nervosa;
· high cholesterol or triglyceride levels (types of fat) in the blood;or
· liver disease brandis accutane journal.
• You may not be able to take Accutane, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove brandis accutane journal.
• Do not take Accutane if you are pregnant or if you could become pregnantduring treatment or for one month after you stop taking Accutane brandis accutane journal. Accutane isin the FDA pregnancy category X brandis accutane journal. This means that Accutane is known to causesevere birth defects in an unborn baby brandis accutane journal. It can also cause miscarriage, prematurebirth, or death of the baby brandis accutane journal. You must take a pregnancy test and have negativeresults when you and your doctor decide that Accutane may be beneficial foryour condition brandis accutane journal. You must have a second pregnancy test with negative resultsduring the first 5 days of the menstrual period right before you start takingAccutane brandis accutane journal. Two reliable forms of birth control must be used at the same time(unless abstinence is the chosen method of birth control or if you have undergonea hysterectomy) for one month before starting treatment with Accutane, duringtreatment with Accutane, and for at least 1 month following the end of treatment brandis accutane journal. You will also be asked to take a pregnancy test on a monthly basis brandis accutane journal. Your doctorwill discuss with you and provide for you a video and written information regardingchoices for birth control, possible causes for birth control failure, and theimportance of using birth control while taking Accutane brandis accutane journal. If you become pregnant,stop using birth control, or miss your menstrual period, immediately stop takingAccutane and notify your doctor brandis accutane journal.
• It is not known whether Accutane passes into breast milk brandis accutane journal. Do not takeAccutane without first talking to your doctor if you are breast-feeding a baby brandis accutane journal.


How should I take Accutane?
• Take Accutane exactly as directed by your doctor brandis accutane journal. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou brandis accutane journal.
• Accutane is a medication taken to treat severe nodular acne that hasnot been helped by other treatments, including antibiotics brandis accutane journal. However, Accutanecan cause serious side effects brandis accutane journal. Before starting treatment with Accutane, discusswith your doctor how bad the acne is, the possible benefits of Accutane andthe possible side effects brandis accutane journal. Your doctor will ask you to read and sign a formindicating that you understand the serious risks associated with Accutane therapy brandis accutane journal.
• You will get no more than a 30-day supply of Accutane at a time brandis accutane journal. Yourprescription should have a special yellow self-adhesive sticker attached toit brandis accutane journal. If your prescription does not have this yellow sticker, call your doctor brandis accutane journal. The pharmacy should not fill the prescription without this sticker brandis accutane journal.
• Take each dose of Accutane with a full glass of water brandis accutane journal. This will helpprevent the medication inside the capsule from irritating the lining of theesophagus brandis accutane journal. For the same reason, do not chew or suck on the capsule brandis accutane journal.
• Take Accutane twice a day with food or milk to get the best results fromthis medication, unless otherwise directed by your doctor brandis accutane journal.
• Take all of the Accutane that has been prescribed for you even if yoursymptoms start to improve brandis accutane journal. The acne may seem to get worse at the start of therapy,but should then begin to improve brandis accutane journal. For the best results, finish all of the medicationthat has been prescribed brandis accutane journal. You may require more than one course of therapy withAccutane brandis accutane journal.
• Your doctor may perform blood tests during treatment with Accutane tomonitor side effects from this medication brandis accutane journal.
• Due to the serious side effects that may occur with the use of this medication,do not share it with anyone else brandis accutane journal.
• Store Accutane at room temperature away from moisture and heat brandis accutane journal.


What happens if I miss a dose?
• Take the missed dose as soon as you remember brandis accutane journal. However, if it is almosttime for the next dose, skip the missed dose and only take the next regularlyscheduled dose brandis accutane journal. Do not take a double dose of this medication brandis accutane journal.


What happens if I overdose?
• Seek emergency medical attention brandis accutane journal.
• Symptoms of an Accutane overdose include vomiting, abdominal pain, flushingof the face, inflammation of the lips, headache, dizziness, and clumsiness brandis accutane journal.


What should I avoid while taking Accutane?
• Do not take vitamin supplements containing vitamin A during treatmentwith Accutane brandis accutane journal. This could cause increased side effects brandis accutane journal.
• Do not donate blood while taking Accutane and for at least 1 month followingthe end of treatment brandis accutane journal. Blood donated while taking Accutane may be given to apregnant woman and be harmful to her baby brandis accutane journal.
• Do not use wax hair removal systems or have any skin resurfacing procedures(such as dermabrasion or laser treatment) performed while taking Accutane andfor six months following treatment due to the possibility of scarring brandis accutane journal.
• Avoid exposure to sunlight or UV rays while taking Accutane brandis accutane journal. Accutanemay increase the sensitivity of the skin to sunlight and a severe sunburn couldresult brandis accutane journal.
• Use caution when driving a vehicle at night brandis accutane journal. Accutane can cause decreasednight vision brandis accutane journal. The onset of decreased night vision may be sudden brandis accutane journal.


What are the possible side effects of Accutane?
• Stop taking Accutane and seek emergency medical attention or contactyour doctor immediately if you experience any of the following serious sideeffects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· changes in vision, blurred vision, or decreased vision (especiallyat night);
· painful or constant dryness of the eyes;
· depression including feelings of sadness, crying spells, irritability,changes in sleep patterns, unusual tiredness, trouble concentrating, loss ofappetite, and/or suicidal thoughts or other mental problems;
· stomach, chest, or bowel pain;
· rectal bleeding, or severe or bloody diarrhea;
· difficulty or pain when swallowing;
· new or worsening heartburn;
· yellowing of the skin or eyes or persistently dark urine;
· severe headache or dizziness;
· seizures;
· nausea and vomiting;
· joint or muscle pain or bone problems;
· hearing problems or hearing loss;
· trouble breathing;
· fainting;
· increased thirst or urination;
· slurred speech or problems moving;
· leg swelling;
· increased levels of cholesterol or triglyceride (types of fat) in yourblood (detected by blood tests) brandis accutane journal.
• Other, less serious side effects are more likely to occur brandis accutane journal. Continue totake Accutane and talk to your doctor if you experience
· inflammation, dryness, or cracking of the lips;
· dry skin, dry mouth, dry or bleeding nose, dryness of the eyes and/ordifficulty wearing contact lenses;
· itching; or
· increased sensitivity of the skin to the sun brandis accutane journal.
• Side effects other than those listed here may also occur brandis accutane journal. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome brandis accutane journal.


What other drugs will affect Accutane?
• Do not take any of the following medicines while taking Accutane:
· vitamin supplements containing vitamin A; or
· a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin,Panmycin, Robitet, others), minocycline (Minocin, Dynacin, Vectrin), doxycycline(Doryx, Monodox, Vibramycin, Vibra-Tabs), demeclocycline (Declomycin), or troleandomycin(TAO) brandis accutane journal.
• Taking any of the drugs listed above during treatment with Accutane maybe dangerous brandis accutane journal.
• Before taking Accutane, tell your doctor if you are taking carbamazepine(Tegretol, Carbatrol, Epitol) brandis accutane journal. You may require a dosage adjustment or specialmonitoring during treatment brandis accutane journal.
• Do not use other acne medications unless otherwise directed by your doctor brandis accutane journal. They may interfere with the treatment or increase irritation of the skin brandis accutane journal.
• Do not take birth control pills that do not contain estrogen ("minipills")during treatment with Accutane brandis accutane journal. They may not work while taking Accutane brandis accutane journal.
• Drugs other than those listed here may also interact with Accutane brandis accutane journal. Talkto your doctor or pharmacist before taking any prescription or over-the-countermedicines, including herbal products brandis accutane journal.


Where can I get more information?
• Your pharmacist has additional information about Accutane written forhealth professionals that you may read brandis accutane journal.


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