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Actonel
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kanis fracture osteoporosis 2004 november
risedronate (rih SEH droe nate)

What is the most important information I should know about Actonel?
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach kanis fracture osteoporosis 2004 november. Do not lie down for atleast 30 minutes after taking a dose of Actonel kanis fracture osteoporosis 2004 november.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements kanis fracture osteoporosis 2004 november. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication kanis fracture osteoporosis 2004 november. This timing is very important in getting the maximum amountof medication from each dose kanis fracture osteoporosis 2004 november. Foods, beverages, and other medications greatlydecrease the effect of Actonel kanis fracture osteoporosis 2004 november.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week kanis fracture osteoporosis 2004 november. Follow your doctor's instructions kanis fracture osteoporosis 2004 november.


What is Actonel?
• Actonel alters the cycle of bone formation and breakdown in the body kanis fracture osteoporosis 2004 november.
• Actonel is used to prevent and treat postmenopausal and steroid-causedbone-thinning (osteoporosis) kanis fracture osteoporosis 2004 november. Actonel is also used to treat Paget's diseaseof bone (osteitis deformans) kanis fracture osteoporosis 2004 november.
• Actonel may also be used for purposes other than those listed in thismedication guide kanis fracture osteoporosis 2004 november.


What should I discuss with my healthcare provider before taking Actonel?
• Do not take Actonel without first talking to your doctor if you
· have a problem swallowing, such as a narrowing of the esophagus;
· have esophageal ulcers or esophageal disease;
· have stomach ulcers or other stomach problems;
· have a condition that causes low levels of calcium in the body;
· have a kidney disease; or
· are unable to stand or sit upright for at least 30 minutes kanis fracture osteoporosis 2004 november.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove kanis fracture osteoporosis 2004 november.
• Actonel is in the FDA pregnancy category C kanis fracture osteoporosis 2004 november. This means that it is notknown whether it will be harmful to an unborn baby kanis fracture osteoporosis 2004 november. Do not take Actonel withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment kanis fracture osteoporosis 2004 november.
• It is not known whether Actonel passes into breast milk kanis fracture osteoporosis 2004 november. Do not takeActonel without first talking to your doctor if you are breast-feeding a baby kanis fracture osteoporosis 2004 november.


How should I take Actonel?
• Take Actonel exactly as directed by your doctor kanis fracture osteoporosis 2004 november. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you kanis fracture osteoporosis 2004 november.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements kanis fracture osteoporosis 2004 november. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication kanis fracture osteoporosis 2004 november. This timing is very important in getting the maximum amountof medication from each dose kanis fracture osteoporosis 2004 november. Foods, beverages, and other medications greatlydecrease the effect of Actonel kanis fracture osteoporosis 2004 november.
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach kanis fracture osteoporosis 2004 november. Do not lie down for atleast 30 minutes after taking a dose of Actonel kanis fracture osteoporosis 2004 november.
• Do not crush, chew, or suck the pills kanis fracture osteoporosis 2004 november. Swallow them whole kanis fracture osteoporosis 2004 november.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week kanis fracture osteoporosis 2004 november. Follow your doctor's instructions kanis fracture osteoporosis 2004 november.
• It is important to maintain adequate amounts of calcium and vitamin Din the diet while taking Actonel kanis fracture osteoporosis 2004 november. Discuss with your doctor appropriate amountsof calcium and vitamin D kanis fracture osteoporosis 2004 november.
• Store Actonel at room temperature away from moisture and heat kanis fracture osteoporosis 2004 november.


What happens if I miss a dose?
• If you take Actonel every day and you miss a dose, skip that dose andtake the next regularly scheduled dose the following day kanis fracture osteoporosis 2004 november. Missing one dose willnot make a difference in the treatment kanis fracture osteoporosis 2004 november.
• If you take Actonel once a week and you miss a dose, take the misseddose the next morning kanis fracture osteoporosis 2004 november. Do not take two tablets on the same day kanis fracture osteoporosis 2004 november. Then, returnto your regular schedule, taking one tablet on the chosen morning of the week kanis fracture osteoporosis 2004 november.


What happens if I overdose?
• Seek emergency medical attention kanis fracture osteoporosis 2004 november.
• The symptoms of a Actonel overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in the abdomen, diarrhea, other stomach-relatedsymptoms, muscle cramps, numbness or tingling, uncontrollable facial grimacing,seizures, irritability, and abnormal behavior kanis fracture osteoporosis 2004 november.


What should I avoid while taking Actonel?
• There are no restrictions on food, beverages, or activity while takingActonel, unless otherwise directed by your doctor kanis fracture osteoporosis 2004 november.


What are the possible side effects of Actonel?
• Stop taking Actonel and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· pain or burning under the ribs or in the back; or
· new or worsening heartburn kanis fracture osteoporosis 2004 november.
• Other, less serious side effects may be more likely to occur kanis fracture osteoporosis 2004 november. Continueto take Actonel and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, or diarrhea;
· headache; or
· muscle or joint soreness or aches kanis fracture osteoporosis 2004 november.
• Side effects other than those listed here may also occur kanis fracture osteoporosis 2004 november. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome kanis fracture osteoporosis 2004 november.


What other drugs will affect Actonel?
• Do not take any other medicine, including vitamins, minerals, or othersupplements, at the same time as Actonel unless otherwise directed by your doctor kanis fracture osteoporosis 2004 november. Any drug that is taken at the same time as Actonel can decrease the effectsof this medicine kanis fracture osteoporosis 2004 november.
• Before taking this medication, tell your doctor if you are taking anyof the following medicines:
· an antacid;
· aspirin; or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others kanis fracture osteoporosis 2004 november.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above kanis fracture osteoporosis 2004 november.
• Drugs other than those listed here may also interact with Actonel kanis fracture osteoporosis 2004 november. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products kanis fracture osteoporosis 2004 november.


Where can I get more information?
• Your pharmacist has more information about Actonel written for healthprofessionals that you may read kanis fracture osteoporosis 2004 november.

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