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milk and osteoporosis evidence
risedronate (rih SEH droe nate)

What is the most important information I should know about Actonel?
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach milk and osteoporosis evidence. Do not lie down for atleast 30 minutes after taking a dose of Actonel milk and osteoporosis evidence.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements milk and osteoporosis evidence. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication milk and osteoporosis evidence. This timing is very important in getting the maximum amountof medication from each dose milk and osteoporosis evidence. Foods, beverages, and other medications greatlydecrease the effect of Actonel milk and osteoporosis evidence.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week milk and osteoporosis evidence. Follow your doctor's instructions milk and osteoporosis evidence.


What is Actonel?
• Actonel alters the cycle of bone formation and breakdown in the body milk and osteoporosis evidence.
• Actonel is used to prevent and treat postmenopausal and steroid-causedbone-thinning (osteoporosis) milk and osteoporosis evidence. Actonel is also used to treat Paget's diseaseof bone (osteitis deformans) milk and osteoporosis evidence.
• Actonel may also be used for purposes other than those listed in thismedication guide milk and osteoporosis evidence.


What should I discuss with my healthcare provider before taking Actonel?
• Do not take Actonel without first talking to your doctor if you
· have a problem swallowing, such as a narrowing of the esophagus;
· have esophageal ulcers or esophageal disease;
· have stomach ulcers or other stomach problems;
· have a condition that causes low levels of calcium in the body;
· have a kidney disease; or
· are unable to stand or sit upright for at least 30 minutes milk and osteoporosis evidence.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove milk and osteoporosis evidence.
• Actonel is in the FDA pregnancy category C milk and osteoporosis evidence. This means that it is notknown whether it will be harmful to an unborn baby milk and osteoporosis evidence. Do not take Actonel withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment milk and osteoporosis evidence.
• It is not known whether Actonel passes into breast milk milk and osteoporosis evidence. Do not takeActonel without first talking to your doctor if you are breast-feeding a baby milk and osteoporosis evidence.


How should I take Actonel?
• Take Actonel exactly as directed by your doctor milk and osteoporosis evidence. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you milk and osteoporosis evidence.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements milk and osteoporosis evidence. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication milk and osteoporosis evidence. This timing is very important in getting the maximum amountof medication from each dose milk and osteoporosis evidence. Foods, beverages, and other medications greatlydecrease the effect of Actonel milk and osteoporosis evidence.
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach milk and osteoporosis evidence. Do not lie down for atleast 30 minutes after taking a dose of Actonel milk and osteoporosis evidence.
• Do not crush, chew, or suck the pills milk and osteoporosis evidence. Swallow them whole milk and osteoporosis evidence.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week milk and osteoporosis evidence. Follow your doctor's instructions milk and osteoporosis evidence.
• It is important to maintain adequate amounts of calcium and vitamin Din the diet while taking Actonel milk and osteoporosis evidence. Discuss with your doctor appropriate amountsof calcium and vitamin D milk and osteoporosis evidence.
• Store Actonel at room temperature away from moisture and heat milk and osteoporosis evidence.


What happens if I miss a dose?
• If you take Actonel every day and you miss a dose, skip that dose andtake the next regularly scheduled dose the following day milk and osteoporosis evidence. Missing one dose willnot make a difference in the treatment milk and osteoporosis evidence.
• If you take Actonel once a week and you miss a dose, take the misseddose the next morning milk and osteoporosis evidence. Do not take two tablets on the same day milk and osteoporosis evidence. Then, returnto your regular schedule, taking one tablet on the chosen morning of the week milk and osteoporosis evidence.


What happens if I overdose?
• Seek emergency medical attention milk and osteoporosis evidence.
• The symptoms of a Actonel overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in the abdomen, diarrhea, other stomach-relatedsymptoms, muscle cramps, numbness or tingling, uncontrollable facial grimacing,seizures, irritability, and abnormal behavior milk and osteoporosis evidence.


What should I avoid while taking Actonel?
• There are no restrictions on food, beverages, or activity while takingActonel, unless otherwise directed by your doctor milk and osteoporosis evidence.


What are the possible side effects of Actonel?
• Stop taking Actonel and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· pain or burning under the ribs or in the back; or
· new or worsening heartburn milk and osteoporosis evidence.
• Other, less serious side effects may be more likely to occur milk and osteoporosis evidence. Continueto take Actonel and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, or diarrhea;
· headache; or
· muscle or joint soreness or aches milk and osteoporosis evidence.
• Side effects other than those listed here may also occur milk and osteoporosis evidence. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome milk and osteoporosis evidence.


What other drugs will affect Actonel?
• Do not take any other medicine, including vitamins, minerals, or othersupplements, at the same time as Actonel unless otherwise directed by your doctor milk and osteoporosis evidence. Any drug that is taken at the same time as Actonel can decrease the effectsof this medicine milk and osteoporosis evidence.
• Before taking this medication, tell your doctor if you are taking anyof the following medicines:
· an antacid;
· aspirin; or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others milk and osteoporosis evidence.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above milk and osteoporosis evidence.
• Drugs other than those listed here may also interact with Actonel milk and osteoporosis evidence. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products milk and osteoporosis evidence.


Where can I get more information?
• Your pharmacist has more information about Actonel written for healthprofessionals that you may read milk and osteoporosis evidence.


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