new osteoporosis treatment research

What is the most important information I should know about Actonel?
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach new osteoporosis treatment research. Do not lie down for atleast 30 minutes after taking a dose of Actonel new osteoporosis treatment research.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements new osteoporosis treatment research. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication new osteoporosis treatment research. This timing is very important in getting the maximum amountof medication from each dose new osteoporosis treatment research. Foods, beverages, and other medications greatlydecrease the effect of Actonel new osteoporosis treatment research.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week new osteoporosis treatment research. Follow your doctor's instructions new osteoporosis treatment research.

What is Actonel?
• Actonel alters the cycle of bone formation and breakdown in the body new osteoporosis treatment research.
• Actonel is used to prevent and treat postmenopausal and steroid-causedbone-thinning (osteoporosis) new osteoporosis treatment research. Actonel is also used to treat Paget's diseaseof bone (osteitis deformans) new osteoporosis treatment research.
• Actonel may also be used for purposes other than those listed in thismedication guide new osteoporosis treatment research.

What should I discuss with my healthcare provider before taking Actonel?
• Do not take Actonel without first talking to your doctor if you
· have a problem swallowing, such as a narrowing of the esophagus;
· have esophageal ulcers or esophageal disease;
· have stomach ulcers or other stomach problems;
· have a condition that causes low levels of calcium in the body;
· have a kidney disease; or
· are unable to stand or sit upright for at least 30 minutes new osteoporosis treatment research.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove new osteoporosis treatment research.
• Actonel is in the FDA pregnancy category C new osteoporosis treatment research. This means that it is notknown whether it will be harmful to an unborn baby new osteoporosis treatment research. Do not take Actonel withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment new osteoporosis treatment research.
• It is not known whether Actonel passes into breast milk new osteoporosis treatment research. Do not takeActonel without first talking to your doctor if you are breast-feeding a baby new osteoporosis treatment research.

How should I take Actonel?
• Take Actonel exactly as directed by your doctor new osteoporosis treatment research. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you new osteoporosis treatment research.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements new osteoporosis treatment research. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication new osteoporosis treatment research. This timing is very important in getting the maximum amountof medication from each dose new osteoporosis treatment research. Foods, beverages, and other medications greatlydecrease the effect of Actonel new osteoporosis treatment research.
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach new osteoporosis treatment research. Do not lie down for atleast 30 minutes after taking a dose of Actonel new osteoporosis treatment research.
• Do not crush, chew, or suck the pills new osteoporosis treatment research. Swallow them whole new osteoporosis treatment research.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week new osteoporosis treatment research. Follow your doctor's instructions new osteoporosis treatment research.
• It is important to maintain adequate amounts of calcium and vitamin Din the diet while taking Actonel new osteoporosis treatment research. Discuss with your doctor appropriate amountsof calcium and vitamin D new osteoporosis treatment research.
• Store Actonel at room temperature away from moisture and heat new osteoporosis treatment research.

What happens if I miss a dose?
• If you take Actonel every day and you miss a dose, skip that dose andtake the next regularly scheduled dose the following day new osteoporosis treatment research. Missing one dose willnot make a difference in the treatment new osteoporosis treatment research.
• If you take Actonel once a week and you miss a dose, take the misseddose the next morning new osteoporosis treatment research. Do not take two tablets on the same day new osteoporosis treatment research. Then, returnto your regular schedule, taking one tablet on the chosen morning of the week new osteoporosis treatment research.

What happens if I overdose?
• Seek emergency medical attention new osteoporosis treatment research.
• The symptoms of a Actonel overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in the abdomen, diarrhea, other stomach-relatedsymptoms, muscle cramps, numbness or tingling, uncontrollable facial grimacing,seizures, irritability, and abnormal behavior new osteoporosis treatment research.

What should I avoid while taking Actonel?
• There are no restrictions on food, beverages, or activity while takingActonel, unless otherwise directed by your doctor new osteoporosis treatment research.

What are the possible side effects of Actonel?
• Stop taking Actonel and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· pain or burning under the ribs or in the back; or
· new or worsening heartburn new osteoporosis treatment research.
• Other, less serious side effects may be more likely to occur new osteoporosis treatment research. Continueto take Actonel and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, or diarrhea;
· headache; or
· muscle or joint soreness or aches new osteoporosis treatment research.
• Side effects other than those listed here may also occur new osteoporosis treatment research. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome new osteoporosis treatment research.

What other drugs will affect Actonel?
• Do not take any other medicine, including vitamins, minerals, or othersupplements, at the same time as Actonel unless otherwise directed by your doctor new osteoporosis treatment research. Any drug that is taken at the same time as Actonel can decrease the effectsof this medicine new osteoporosis treatment research.
• Before taking this medication, tell your doctor if you are taking anyof the following medicines:
· an antacid;
· aspirin; or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others new osteoporosis treatment research.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above new osteoporosis treatment research.
• Drugs other than those listed here may also interact with Actonel new osteoporosis treatment research. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products new osteoporosis treatment research.

Where can I get more information?
• Your pharmacist has more information about Actonel written for healthprofessionals that you may read new osteoporosis treatment research.

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