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osteoporosis international
risedronate (rih SEH droe nate)

What is the most important information I should know about Actonel?
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach osteoporosis international. Do not lie down for atleast 30 minutes after taking a dose of Actonel osteoporosis international.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements osteoporosis international. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication osteoporosis international. This timing is very important in getting the maximum amountof medication from each dose osteoporosis international. Foods, beverages, and other medications greatlydecrease the effect of Actonel osteoporosis international.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week osteoporosis international. Follow your doctor's instructions osteoporosis international.


What is Actonel?
• Actonel alters the cycle of bone formation and breakdown in the body osteoporosis international.
• Actonel is used to prevent and treat postmenopausal and steroid-causedbone-thinning (osteoporosis) osteoporosis international. Actonel is also used to treat Paget's diseaseof bone (osteitis deformans) osteoporosis international.
• Actonel may also be used for purposes other than those listed in thismedication guide osteoporosis international.


What should I discuss with my healthcare provider before taking Actonel?
• Do not take Actonel without first talking to your doctor if you
· have a problem swallowing, such as a narrowing of the esophagus;
· have esophageal ulcers or esophageal disease;
· have stomach ulcers or other stomach problems;
· have a condition that causes low levels of calcium in the body;
· have a kidney disease; or
· are unable to stand or sit upright for at least 30 minutes osteoporosis international.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove osteoporosis international.
• Actonel is in the FDA pregnancy category C osteoporosis international. This means that it is notknown whether it will be harmful to an unborn baby osteoporosis international. Do not take Actonel withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment osteoporosis international.
• It is not known whether Actonel passes into breast milk osteoporosis international. Do not takeActonel without first talking to your doctor if you are breast-feeding a baby osteoporosis international.


How should I take Actonel?
• Take Actonel exactly as directed by your doctor osteoporosis international. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you osteoporosis international.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements osteoporosis international. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication osteoporosis international. This timing is very important in getting the maximum amountof medication from each dose osteoporosis international. Foods, beverages, and other medications greatlydecrease the effect of Actonel osteoporosis international.
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach osteoporosis international. Do not lie down for atleast 30 minutes after taking a dose of Actonel osteoporosis international.
• Do not crush, chew, or suck the pills osteoporosis international. Swallow them whole osteoporosis international.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week osteoporosis international. Follow your doctor's instructions osteoporosis international.
• It is important to maintain adequate amounts of calcium and vitamin Din the diet while taking Actonel osteoporosis international. Discuss with your doctor appropriate amountsof calcium and vitamin D osteoporosis international.
• Store Actonel at room temperature away from moisture and heat osteoporosis international.


What happens if I miss a dose?
• If you take Actonel every day and you miss a dose, skip that dose andtake the next regularly scheduled dose the following day osteoporosis international. Missing one dose willnot make a difference in the treatment osteoporosis international.
• If you take Actonel once a week and you miss a dose, take the misseddose the next morning osteoporosis international. Do not take two tablets on the same day osteoporosis international. Then, returnto your regular schedule, taking one tablet on the chosen morning of the week osteoporosis international.


What happens if I overdose?
• Seek emergency medical attention osteoporosis international.
• The symptoms of a Actonel overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in the abdomen, diarrhea, other stomach-relatedsymptoms, muscle cramps, numbness or tingling, uncontrollable facial grimacing,seizures, irritability, and abnormal behavior osteoporosis international.


What should I avoid while taking Actonel?
• There are no restrictions on food, beverages, or activity while takingActonel, unless otherwise directed by your doctor osteoporosis international.


What are the possible side effects of Actonel?
• Stop taking Actonel and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· pain or burning under the ribs or in the back; or
· new or worsening heartburn osteoporosis international.
• Other, less serious side effects may be more likely to occur osteoporosis international. Continueto take Actonel and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, or diarrhea;
· headache; or
· muscle or joint soreness or aches osteoporosis international.
• Side effects other than those listed here may also occur osteoporosis international. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome osteoporosis international.


What other drugs will affect Actonel?
• Do not take any other medicine, including vitamins, minerals, or othersupplements, at the same time as Actonel unless otherwise directed by your doctor osteoporosis international. Any drug that is taken at the same time as Actonel can decrease the effectsof this medicine osteoporosis international.
• Before taking this medication, tell your doctor if you are taking anyof the following medicines:
· an antacid;
· aspirin; or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others osteoporosis international.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above osteoporosis international.
• Drugs other than those listed here may also interact with Actonel osteoporosis international. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products osteoporosis international.


Where can I get more information?
• Your pharmacist has more information about Actonel written for healthprofessionals that you may read osteoporosis international.


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