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osteoporosis risk factors menopause
risedronate (rih SEH droe nate)

What is the most important information I should know about Actonel?
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach osteoporosis risk factors menopause. Do not lie down for atleast 30 minutes after taking a dose of Actonel osteoporosis risk factors menopause.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements osteoporosis risk factors menopause. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication osteoporosis risk factors menopause. This timing is very important in getting the maximum amountof medication from each dose osteoporosis risk factors menopause. Foods, beverages, and other medications greatlydecrease the effect of Actonel osteoporosis risk factors menopause.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week osteoporosis risk factors menopause. Follow your doctor's instructions osteoporosis risk factors menopause.

What is Actonel?
• Actonel alters the cycle of bone formation and breakdown in the body osteoporosis risk factors menopause.
• Actonel is used to prevent and treat postmenopausal and steroid-causedbone-thinning (osteoporosis) osteoporosis risk factors menopause. Actonel is also used to treat Paget's diseaseof bone (osteitis deformans) osteoporosis risk factors menopause.
• Actonel may also be used for purposes other than those listed in thismedication guide osteoporosis risk factors menopause.

What should I discuss with my healthcare provider before taking Actonel?
• Do not take Actonel without first talking to your doctor if you
· have a problem swallowing, such as a narrowing of the esophagus;
· have esophageal ulcers or esophageal disease;
· have stomach ulcers or other stomach problems;
· have a condition that causes low levels of calcium in the body;
· have a kidney disease; or
· are unable to stand or sit upright for at least 30 minutes osteoporosis risk factors menopause.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove osteoporosis risk factors menopause.
• Actonel is in the FDA pregnancy category C osteoporosis risk factors menopause. This means that it is notknown whether it will be harmful to an unborn baby osteoporosis risk factors menopause. Do not take Actonel withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment osteoporosis risk factors menopause.
• It is not known whether Actonel passes into breast milk osteoporosis risk factors menopause. Do not takeActonel without first talking to your doctor if you are breast-feeding a baby osteoporosis risk factors menopause.

How should I take Actonel?
• Take Actonel exactly as directed by your doctor osteoporosis risk factors menopause. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you osteoporosis risk factors menopause.
• Take Actonel in the morning with a full glass (6 to 8 ounces) of tapwater or bottled water at least 30 minutes before eating any food, drinkingany liquid (other than water), or taking any other medicines including vitamins,minerals, or other supplements osteoporosis risk factors menopause. Do not take Actonel with mineral water, juice,or any other beverage since these beverages may decrease the effectiveness ofthe medication osteoporosis risk factors menopause. This timing is very important in getting the maximum amountof medication from each dose osteoporosis risk factors menopause. Foods, beverages, and other medications greatlydecrease the effect of Actonel osteoporosis risk factors menopause.
• Although it has been reported less frequently with Actonel, other similardrugs can be very damaging to the mouth and stomach osteoporosis risk factors menopause. Do not lie down for atleast 30 minutes after taking a dose of Actonel osteoporosis risk factors menopause.
• Do not crush, chew, or suck the pills osteoporosis risk factors menopause. Swallow them whole osteoporosis risk factors menopause.
• The 35 mg Actonel tablets should only be taken once a week, preferablyon the same day each week osteoporosis risk factors menopause. Follow your doctor's instructions osteoporosis risk factors menopause.
• It is important to maintain adequate amounts of calcium and vitamin Din the diet while taking Actonel osteoporosis risk factors menopause. Discuss with your doctor appropriate amountsof calcium and vitamin D osteoporosis risk factors menopause.
• Store Actonel at room temperature away from moisture and heat osteoporosis risk factors menopause.

What happens if I miss a dose?
• If you take Actonel every day and you miss a dose, skip that dose andtake the next regularly scheduled dose the following day osteoporosis risk factors menopause. Missing one dose willnot make a difference in the treatment osteoporosis risk factors menopause.
• If you take Actonel once a week and you miss a dose, take the misseddose the next morning osteoporosis risk factors menopause. Do not take two tablets on the same day osteoporosis risk factors menopause. Then, returnto your regular schedule, taking one tablet on the chosen morning of the week osteoporosis risk factors menopause.

What happens if I overdose?
• Seek emergency medical attention osteoporosis risk factors menopause.
• The symptoms of a Actonel overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in the abdomen, diarrhea, other stomach-relatedsymptoms, muscle cramps, numbness or tingling, uncontrollable facial grimacing,seizures, irritability, and abnormal behavior osteoporosis risk factors menopause.

What should I avoid while taking Actonel?
• There are no restrictions on food, beverages, or activity while takingActonel, unless otherwise directed by your doctor osteoporosis risk factors menopause.

What are the possible side effects of Actonel?
• Stop taking Actonel and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· pain or burning under the ribs or in the back; or
· new or worsening heartburn osteoporosis risk factors menopause.
• Other, less serious side effects may be more likely to occur osteoporosis risk factors menopause. Continueto take Actonel and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, or diarrhea;
· headache; or
· muscle or joint soreness or aches osteoporosis risk factors menopause.
• Side effects other than those listed here may also occur osteoporosis risk factors menopause. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome osteoporosis risk factors menopause.

What other drugs will affect Actonel?
• Do not take any other medicine, including vitamins, minerals, or othersupplements, at the same time as Actonel unless otherwise directed by your doctor osteoporosis risk factors menopause. Any drug that is taken at the same time as Actonel can decrease the effectsof this medicine osteoporosis risk factors menopause.
• Before taking this medication, tell your doctor if you are taking anyof the following medicines:
· an antacid;
· aspirin; or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others osteoporosis risk factors menopause.
• You may not be able to take Actonel, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above osteoporosis risk factors menopause.
• Drugs other than those listed here may also interact with Actonel osteoporosis risk factors menopause. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products osteoporosis risk factors menopause.

Where can I get more information?
• Your pharmacist has more information about Actonel written for healthprofessionals that you may read osteoporosis risk factors menopause.

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