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acto sd2 804
Pioglitazone (pie oh GLIH ta zone)

What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos acto sd2 804. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine acto sd2 804. These symptoms may be early signs of liverproblems acto sd2 804.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos acto sd2 804. These may be early symptoms of heart problems acto sd2 804.
• Actos usually does not cause hypoglycemia (low blood sugar) acto sd2 804. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos acto sd2 804. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea acto sd2 804. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar acto sd2 804.
• Actos may decrease the effects of some birth control pills acto sd2 804. Additionalmeasures may be necessary to prevent pregnancy while taking Actos acto sd2 804. Talk to yourdoctor about the use of birth control acto sd2 804.


What is Actos?
• Actos is an antihyperglycemic agent acto sd2 804. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver acto sd2 804. It canhelp control blood sugar levels acto sd2 804.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) acto sd2 804. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control acto sd2 804.
• Actos may also be used for purposes other than those listed in this medicationguide acto sd2 804.


What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease acto sd2 804.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery acto sd2 804.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove acto sd2 804.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos acto sd2 804. Therefore, pregnancy mayoccur and birth control may be a consideration acto sd2 804.
• Actos is in the FDA pregnancy category C acto sd2 804. This means that it is not knownwhether Actos will be harmful to an unborn baby acto sd2 804. Generally, insulin is the drugof choice for controlling diabetes during pregnancy acto sd2 804. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment acto sd2 804.
• It is not known whether Actos passes into breast milk acto sd2 804. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby acto sd2 804.
• The safety and effectiveness of Actos have not been established for children acto sd2 804.


How should I take Actos?
• Take Actos exactly as directed by your doctor acto sd2 804. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou acto sd2 804.
• Take each dose with a full glass of water acto sd2 804.
• Actos can be taken with or without food or meals acto sd2 804.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos acto sd2 804. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine acto sd2 804. These symptoms may be early signs of liverproblems acto sd2 804.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption acto sd2 804. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea acto sd2 804. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar acto sd2 804.
• Store Actos at room temperature away from moisture and heat acto sd2 804.


What happens if I miss a dose?
• Take the missed dose as soon as you remember acto sd2 804. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose acto sd2 804. Do not take a double dose acto sd2 804.


What happens if I overdose?
• Seek emergency medical attention acto sd2 804.
• Symptoms of a Actos overdose are not known acto sd2 804.


What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely acto sd2 804. Changingany of these factors can affect blood sugar levels acto sd2 804.
• Avoid alcohol acto sd2 804. It lowers blood sugar and may interfere with diabetestreatment acto sd2 804.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery acto sd2 804.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor acto sd2 804.


What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine acto sd2 804.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos acto sd2 804. These may be early symptoms of heart problems acto sd2 804.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption acto sd2 804. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea acto sd2 804. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar acto sd2 804.
• Other less serious side effects may also occur acto sd2 804. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms acto sd2 804.
• Side effects other than those listed here may also occur acto sd2 804. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome acto sd2 804.


What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills acto sd2 804. Additionalmeasures may be necessary to prevent pregnancy while taking Actos acto sd2 804. Talk to yourdoctor about the use of birth control acto sd2 804.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) acto sd2 804. Ketoconazole may interact with Actos acto sd2 804.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor acto sd2 804.
• Drugs other than those listed here may also interact with Actos or affectyour condition acto sd2 804. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products acto sd2 804.


Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read acto sd2 804.


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