actos mechanism of action
Pioglitazone (pie oh GLIH ta zone)
What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos actos mechanism of action. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine actos mechanism of action. These symptoms may be early signs of liverproblems actos mechanism of action.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos actos mechanism of action. These may be early symptoms of heart problems actos mechanism of action.
• Actos usually does not cause hypoglycemia (low blood sugar) actos mechanism of action. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos actos mechanism of action. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea actos mechanism of action. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar actos mechanism of action.
• Actos may decrease the effects of some birth control pills actos mechanism of action. Additionalmeasures may be necessary to prevent pregnancy while taking Actos actos mechanism of action. Talk to yourdoctor about the use of birth control actos mechanism of action.
What is Actos?
• Actos is an antihyperglycemic agent actos mechanism of action. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver actos mechanism of action. It canhelp control blood sugar levels actos mechanism of action.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) actos mechanism of action. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control actos mechanism of action.
• Actos may also be used for purposes other than those listed in this medicationguide actos mechanism of action.
What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease actos mechanism of action.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery actos mechanism of action.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove actos mechanism of action.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos actos mechanism of action. Therefore, pregnancy mayoccur and birth control may be a consideration actos mechanism of action.
• Actos is in the FDA pregnancy category C actos mechanism of action. This means that it is not knownwhether Actos will be harmful to an unborn baby actos mechanism of action. Generally, insulin is the drugof choice for controlling diabetes during pregnancy actos mechanism of action. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment actos mechanism of action.
• It is not known whether Actos passes into breast milk actos mechanism of action. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby actos mechanism of action.
• The safety and effectiveness of Actos have not been established for children actos mechanism of action.
How should I take Actos?
• Take Actos exactly as directed by your doctor actos mechanism of action. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou actos mechanism of action.
• Take each dose with a full glass of water actos mechanism of action.
• Actos can be taken with or without food or meals actos mechanism of action.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos actos mechanism of action. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine actos mechanism of action. These symptoms may be early signs of liverproblems actos mechanism of action.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption actos mechanism of action. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea actos mechanism of action. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar actos mechanism of action.
• Store Actos at room temperature away from moisture and heat actos mechanism of action.
What happens if I miss a dose?
• Take the missed dose as soon as you remember actos mechanism of action. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose actos mechanism of action. Do not take a double dose actos mechanism of action.
What happens if I overdose?
• Seek emergency medical attention actos mechanism of action.
• Symptoms of a Actos overdose are not known actos mechanism of action.
What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely actos mechanism of action. Changingany of these factors can affect blood sugar levels actos mechanism of action.
• Avoid alcohol actos mechanism of action. It lowers blood sugar and may interfere with diabetestreatment actos mechanism of action.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery actos mechanism of action.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor actos mechanism of action.
What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine actos mechanism of action.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos actos mechanism of action. These may be early symptoms of heart problems actos mechanism of action.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption actos mechanism of action. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea actos mechanism of action. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar actos mechanism of action.
• Other less serious side effects may also occur actos mechanism of action. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms actos mechanism of action.
• Side effects other than those listed here may also occur actos mechanism of action. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome actos mechanism of action.
What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills actos mechanism of action. Additionalmeasures may be necessary to prevent pregnancy while taking Actos actos mechanism of action. Talk to yourdoctor about the use of birth control actos mechanism of action.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) actos mechanism of action. Ketoconazole may interact with Actos actos mechanism of action.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor actos mechanism of action.
• Drugs other than those listed here may also interact with Actos or affectyour condition actos mechanism of action. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products actos mechanism of action.
Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read actos mechanism of action.
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