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Pioglitazone (pie oh GLIH ta zone)

What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos beanie actos drug. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine beanie actos drug. These symptoms may be early signs of liverproblems beanie actos drug.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos beanie actos drug. These may be early symptoms of heart problems beanie actos drug.
• Actos usually does not cause hypoglycemia (low blood sugar) beanie actos drug. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos beanie actos drug. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea beanie actos drug. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar beanie actos drug.
• Actos may decrease the effects of some birth control pills beanie actos drug. Additionalmeasures may be necessary to prevent pregnancy while taking Actos beanie actos drug. Talk to yourdoctor about the use of birth control beanie actos drug.


What is Actos?
• Actos is an antihyperglycemic agent beanie actos drug. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver beanie actos drug. It canhelp control blood sugar levels beanie actos drug.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) beanie actos drug. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control beanie actos drug.
• Actos may also be used for purposes other than those listed in this medicationguide beanie actos drug.


What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease beanie actos drug.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery beanie actos drug.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove beanie actos drug.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos beanie actos drug. Therefore, pregnancy mayoccur and birth control may be a consideration beanie actos drug.
• Actos is in the FDA pregnancy category C beanie actos drug. This means that it is not knownwhether Actos will be harmful to an unborn baby beanie actos drug. Generally, insulin is the drugof choice for controlling diabetes during pregnancy beanie actos drug. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment beanie actos drug.
• It is not known whether Actos passes into breast milk beanie actos drug. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby beanie actos drug.
• The safety and effectiveness of Actos have not been established for children beanie actos drug.


How should I take Actos?
• Take Actos exactly as directed by your doctor beanie actos drug. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou beanie actos drug.
• Take each dose with a full glass of water beanie actos drug.
• Actos can be taken with or without food or meals beanie actos drug.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos beanie actos drug. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine beanie actos drug. These symptoms may be early signs of liverproblems beanie actos drug.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption beanie actos drug. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea beanie actos drug. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar beanie actos drug.
• Store Actos at room temperature away from moisture and heat beanie actos drug.


What happens if I miss a dose?
• Take the missed dose as soon as you remember beanie actos drug. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose beanie actos drug. Do not take a double dose beanie actos drug.


What happens if I overdose?
• Seek emergency medical attention beanie actos drug.
• Symptoms of a Actos overdose are not known beanie actos drug.


What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely beanie actos drug. Changingany of these factors can affect blood sugar levels beanie actos drug.
• Avoid alcohol beanie actos drug. It lowers blood sugar and may interfere with diabetestreatment beanie actos drug.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery beanie actos drug.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor beanie actos drug.


What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine beanie actos drug.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos beanie actos drug. These may be early symptoms of heart problems beanie actos drug.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption beanie actos drug. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea beanie actos drug. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar beanie actos drug.
• Other less serious side effects may also occur beanie actos drug. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms beanie actos drug.
• Side effects other than those listed here may also occur beanie actos drug. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome beanie actos drug.


What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills beanie actos drug. Additionalmeasures may be necessary to prevent pregnancy while taking Actos beanie actos drug. Talk to yourdoctor about the use of birth control beanie actos drug.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) beanie actos drug. Ketoconazole may interact with Actos beanie actos drug.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor beanie actos drug.
• Drugs other than those listed here may also interact with Actos or affectyour condition beanie actos drug. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products beanie actos drug.


Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read beanie actos drug.


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