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What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos el color de nuestra piel acto primero. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine el color de nuestra piel acto primero. These symptoms may be early signs of liverproblems el color de nuestra piel acto primero.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos el color de nuestra piel acto primero. These may be early symptoms of heart problems el color de nuestra piel acto primero.
• Actos usually does not cause hypoglycemia (low blood sugar) el color de nuestra piel acto primero. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos el color de nuestra piel acto primero. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea el color de nuestra piel acto primero. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar el color de nuestra piel acto primero.
• Actos may decrease the effects of some birth control pills el color de nuestra piel acto primero. Additionalmeasures may be necessary to prevent pregnancy while taking Actos el color de nuestra piel acto primero. Talk to yourdoctor about the use of birth control el color de nuestra piel acto primero.

What is Actos?
• Actos is an antihyperglycemic agent el color de nuestra piel acto primero. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver el color de nuestra piel acto primero. It canhelp control blood sugar levels el color de nuestra piel acto primero.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) el color de nuestra piel acto primero. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control el color de nuestra piel acto primero.
• Actos may also be used for purposes other than those listed in this medicationguide el color de nuestra piel acto primero.

What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease el color de nuestra piel acto primero.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery el color de nuestra piel acto primero.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove el color de nuestra piel acto primero.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos el color de nuestra piel acto primero. Therefore, pregnancy mayoccur and birth control may be a consideration el color de nuestra piel acto primero.
• Actos is in the FDA pregnancy category C el color de nuestra piel acto primero. This means that it is not knownwhether Actos will be harmful to an unborn baby el color de nuestra piel acto primero. Generally, insulin is the drugof choice for controlling diabetes during pregnancy el color de nuestra piel acto primero. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment el color de nuestra piel acto primero.
• It is not known whether Actos passes into breast milk el color de nuestra piel acto primero. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby el color de nuestra piel acto primero.
• The safety and effectiveness of Actos have not been established for children el color de nuestra piel acto primero.

How should I take Actos?
• Take Actos exactly as directed by your doctor el color de nuestra piel acto primero. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou el color de nuestra piel acto primero.
• Take each dose with a full glass of water el color de nuestra piel acto primero.
• Actos can be taken with or without food or meals el color de nuestra piel acto primero.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos el color de nuestra piel acto primero. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine el color de nuestra piel acto primero. These symptoms may be early signs of liverproblems el color de nuestra piel acto primero.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption el color de nuestra piel acto primero. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea el color de nuestra piel acto primero. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar el color de nuestra piel acto primero.
• Store Actos at room temperature away from moisture and heat el color de nuestra piel acto primero.

What happens if I miss a dose?
• Take the missed dose as soon as you remember el color de nuestra piel acto primero. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose el color de nuestra piel acto primero. Do not take a double dose el color de nuestra piel acto primero.

What happens if I overdose?
• Seek emergency medical attention el color de nuestra piel acto primero.
• Symptoms of a Actos overdose are not known el color de nuestra piel acto primero.

What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely el color de nuestra piel acto primero. Changingany of these factors can affect blood sugar levels el color de nuestra piel acto primero.
• Avoid alcohol el color de nuestra piel acto primero. It lowers blood sugar and may interfere with diabetestreatment el color de nuestra piel acto primero.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery el color de nuestra piel acto primero.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor el color de nuestra piel acto primero.

What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine el color de nuestra piel acto primero.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos el color de nuestra piel acto primero. These may be early symptoms of heart problems el color de nuestra piel acto primero.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption el color de nuestra piel acto primero. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea el color de nuestra piel acto primero. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar el color de nuestra piel acto primero.
• Other less serious side effects may also occur el color de nuestra piel acto primero. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms el color de nuestra piel acto primero.
• Side effects other than those listed here may also occur el color de nuestra piel acto primero. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome el color de nuestra piel acto primero.

What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills el color de nuestra piel acto primero. Additionalmeasures may be necessary to prevent pregnancy while taking Actos el color de nuestra piel acto primero. Talk to yourdoctor about the use of birth control el color de nuestra piel acto primero.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) el color de nuestra piel acto primero. Ketoconazole may interact with Actos el color de nuestra piel acto primero.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor el color de nuestra piel acto primero.
• Drugs other than those listed here may also interact with Actos or affectyour condition el color de nuestra piel acto primero. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products el color de nuestra piel acto primero.

Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read el color de nuestra piel acto primero.

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