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What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos fotos del acto final del frente amplio. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine fotos del acto final del frente amplio. These symptoms may be early signs of liverproblems fotos del acto final del frente amplio.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos fotos del acto final del frente amplio. These may be early symptoms of heart problems fotos del acto final del frente amplio.
• Actos usually does not cause hypoglycemia (low blood sugar) fotos del acto final del frente amplio. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos fotos del acto final del frente amplio. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea fotos del acto final del frente amplio. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar fotos del acto final del frente amplio.
• Actos may decrease the effects of some birth control pills fotos del acto final del frente amplio. Additionalmeasures may be necessary to prevent pregnancy while taking Actos fotos del acto final del frente amplio. Talk to yourdoctor about the use of birth control fotos del acto final del frente amplio.

What is Actos?
• Actos is an antihyperglycemic agent fotos del acto final del frente amplio. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver fotos del acto final del frente amplio. It canhelp control blood sugar levels fotos del acto final del frente amplio.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) fotos del acto final del frente amplio. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control fotos del acto final del frente amplio.
• Actos may also be used for purposes other than those listed in this medicationguide fotos del acto final del frente amplio.

What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease fotos del acto final del frente amplio.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery fotos del acto final del frente amplio.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove fotos del acto final del frente amplio.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos fotos del acto final del frente amplio. Therefore, pregnancy mayoccur and birth control may be a consideration fotos del acto final del frente amplio.
• Actos is in the FDA pregnancy category C fotos del acto final del frente amplio. This means that it is not knownwhether Actos will be harmful to an unborn baby fotos del acto final del frente amplio. Generally, insulin is the drugof choice for controlling diabetes during pregnancy fotos del acto final del frente amplio. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment fotos del acto final del frente amplio.
• It is not known whether Actos passes into breast milk fotos del acto final del frente amplio. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby fotos del acto final del frente amplio.
• The safety and effectiveness of Actos have not been established for children fotos del acto final del frente amplio.

How should I take Actos?
• Take Actos exactly as directed by your doctor fotos del acto final del frente amplio. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou fotos del acto final del frente amplio.
• Take each dose with a full glass of water fotos del acto final del frente amplio.
• Actos can be taken with or without food or meals fotos del acto final del frente amplio.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos fotos del acto final del frente amplio. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine fotos del acto final del frente amplio. These symptoms may be early signs of liverproblems fotos del acto final del frente amplio.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption fotos del acto final del frente amplio. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea fotos del acto final del frente amplio. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar fotos del acto final del frente amplio.
• Store Actos at room temperature away from moisture and heat fotos del acto final del frente amplio.

What happens if I miss a dose?
• Take the missed dose as soon as you remember fotos del acto final del frente amplio. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose fotos del acto final del frente amplio. Do not take a double dose fotos del acto final del frente amplio.

What happens if I overdose?
• Seek emergency medical attention fotos del acto final del frente amplio.
• Symptoms of a Actos overdose are not known fotos del acto final del frente amplio.

What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely fotos del acto final del frente amplio. Changingany of these factors can affect blood sugar levels fotos del acto final del frente amplio.
• Avoid alcohol fotos del acto final del frente amplio. It lowers blood sugar and may interfere with diabetestreatment fotos del acto final del frente amplio.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery fotos del acto final del frente amplio.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor fotos del acto final del frente amplio.

What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine fotos del acto final del frente amplio.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos fotos del acto final del frente amplio. These may be early symptoms of heart problems fotos del acto final del frente amplio.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption fotos del acto final del frente amplio. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea fotos del acto final del frente amplio. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar fotos del acto final del frente amplio.
• Other less serious side effects may also occur fotos del acto final del frente amplio. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms fotos del acto final del frente amplio.
• Side effects other than those listed here may also occur fotos del acto final del frente amplio. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome fotos del acto final del frente amplio.

What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills fotos del acto final del frente amplio. Additionalmeasures may be necessary to prevent pregnancy while taking Actos fotos del acto final del frente amplio. Talk to yourdoctor about the use of birth control fotos del acto final del frente amplio.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) fotos del acto final del frente amplio. Ketoconazole may interact with Actos fotos del acto final del frente amplio.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor fotos del acto final del frente amplio.
• Drugs other than those listed here may also interact with Actos or affectyour condition fotos del acto final del frente amplio. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products fotos del acto final del frente amplio.

Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read fotos del acto final del frente amplio.

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