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hecho y acto juridico
Pioglitazone (pie oh GLIH ta zone)

What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos hecho y acto juridico. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine hecho y acto juridico. These symptoms may be early signs of liverproblems hecho y acto juridico.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos hecho y acto juridico. These may be early symptoms of heart problems hecho y acto juridico.
• Actos usually does not cause hypoglycemia (low blood sugar) hecho y acto juridico. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos hecho y acto juridico. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea hecho y acto juridico. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar hecho y acto juridico.
• Actos may decrease the effects of some birth control pills hecho y acto juridico. Additionalmeasures may be necessary to prevent pregnancy while taking Actos hecho y acto juridico. Talk to yourdoctor about the use of birth control hecho y acto juridico.


What is Actos?
• Actos is an antihyperglycemic agent hecho y acto juridico. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver hecho y acto juridico. It canhelp control blood sugar levels hecho y acto juridico.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) hecho y acto juridico. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control hecho y acto juridico.
• Actos may also be used for purposes other than those listed in this medicationguide hecho y acto juridico.


What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease hecho y acto juridico.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery hecho y acto juridico.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove hecho y acto juridico.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos hecho y acto juridico. Therefore, pregnancy mayoccur and birth control may be a consideration hecho y acto juridico.
• Actos is in the FDA pregnancy category C hecho y acto juridico. This means that it is not knownwhether Actos will be harmful to an unborn baby hecho y acto juridico. Generally, insulin is the drugof choice for controlling diabetes during pregnancy hecho y acto juridico. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment hecho y acto juridico.
• It is not known whether Actos passes into breast milk hecho y acto juridico. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby hecho y acto juridico.
• The safety and effectiveness of Actos have not been established for children hecho y acto juridico.


How should I take Actos?
• Take Actos exactly as directed by your doctor hecho y acto juridico. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou hecho y acto juridico.
• Take each dose with a full glass of water hecho y acto juridico.
• Actos can be taken with or without food or meals hecho y acto juridico.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos hecho y acto juridico. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine hecho y acto juridico. These symptoms may be early signs of liverproblems hecho y acto juridico.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption hecho y acto juridico. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea hecho y acto juridico. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar hecho y acto juridico.
• Store Actos at room temperature away from moisture and heat hecho y acto juridico.


What happens if I miss a dose?
• Take the missed dose as soon as you remember hecho y acto juridico. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose hecho y acto juridico. Do not take a double dose hecho y acto juridico.


What happens if I overdose?
• Seek emergency medical attention hecho y acto juridico.
• Symptoms of a Actos overdose are not known hecho y acto juridico.


What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely hecho y acto juridico. Changingany of these factors can affect blood sugar levels hecho y acto juridico.
• Avoid alcohol hecho y acto juridico. It lowers blood sugar and may interfere with diabetestreatment hecho y acto juridico.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery hecho y acto juridico.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor hecho y acto juridico.


What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine hecho y acto juridico.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos hecho y acto juridico. These may be early symptoms of heart problems hecho y acto juridico.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption hecho y acto juridico. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea hecho y acto juridico. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar hecho y acto juridico.
• Other less serious side effects may also occur hecho y acto juridico. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms hecho y acto juridico.
• Side effects other than those listed here may also occur hecho y acto juridico. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hecho y acto juridico.


What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills hecho y acto juridico. Additionalmeasures may be necessary to prevent pregnancy while taking Actos hecho y acto juridico. Talk to yourdoctor about the use of birth control hecho y acto juridico.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) hecho y acto juridico. Ketoconazole may interact with Actos hecho y acto juridico.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor hecho y acto juridico.
• Drugs other than those listed here may also interact with Actos or affectyour condition hecho y acto juridico. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products hecho y acto juridico.


Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read hecho y acto juridico.


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