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Pioglitazone (pie oh GLIH ta zone)

What is the most important information I should know about Actos?
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos menominee termination acto. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine menominee termination acto. These symptoms may be early signs of liverproblems menominee termination acto.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (water retention), shortness of breath, or chest pain duringtreatment with Actos menominee termination acto. These may be early symptoms of heart problems menominee termination acto.
• Actos usually does not cause hypoglycemia (low blood sugar) menominee termination acto. However,hypoglycemia may occur as a result of skipped meals, excessive exercise, oralcohol consumption while taking Actos menominee termination acto. Know the signs and symptoms of hypoglycemia,which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea menominee termination acto. Carry hard candy or glucose tablets with you to treat episodesof low blood sugar menominee termination acto.
• Actos may decrease the effects of some birth control pills menominee termination acto. Additionalmeasures may be necessary to prevent pregnancy while taking Actos menominee termination acto. Talk to yourdoctor about the use of birth control menominee termination acto.


What is Actos?
• Actos is an antihyperglycemic agent menominee termination acto. It helps the body respond betterto insulin and it reduces the amount of sugar produced by the liver menominee termination acto. It canhelp control blood sugar levels menominee termination acto.
• Actos is used, along with diet and exercise, in the treatment of non-insulin-dependentdiabetes mellitus (type II diabetes) menominee termination acto. Actos may also be used with a sulfonylurea(e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulinwhen diet and exercise plus any one of these medicines alone do not result inadequate blood sugar control menominee termination acto.
• Actos may also be used for purposes other than those listed in this medicationguide menominee termination acto.


What should I discuss with my healthcare provider before taking Actos?
• Do not take Actos without first talking to your doctor if you have liverdisease menominee termination acto.
• Before taking this medication, tell your doctor if you
· have heart failure or heart disease;
· have edema (water retention or swelling);
· have type 1 diabetes mellitus (insulin-dependent diabetes);
· have a serious infection, illness, or injury; or
· need surgery menominee termination acto.
• You may not be able to take Actos, or you may need a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove menominee termination acto.
• Treatment with Actos may cause resumption of fertility by allowing forthe return of ovulation (production of eggs) in certain women with insulin resistancewho were not ovulating before treatment with Actos menominee termination acto. Therefore, pregnancy mayoccur and birth control may be a consideration menominee termination acto.
• Actos is in the FDA pregnancy category C menominee termination acto. This means that it is not knownwhether Actos will be harmful to an unborn baby menominee termination acto. Generally, insulin is the drugof choice for controlling diabetes during pregnancy menominee termination acto. Do not take Actos withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment menominee termination acto.
• It is not known whether Actos passes into breast milk menominee termination acto. Do not take Actoswithout first talking to your doctor if you are breast-feeding a baby menominee termination acto.
• The safety and effectiveness of Actos have not been established for children menominee termination acto.


How should I take Actos?
• Take Actos exactly as directed by your doctor menominee termination acto. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou menominee termination acto.
• Take each dose with a full glass of water menominee termination acto.
• Actos can be taken with or without food or meals menominee termination acto.
• Usually, liver function is monitored with blood tests at the start oftreatment, every two months for the first year of treatment, and periodicallythereafter during treatment with Actos menominee termination acto. Notify your doctor immediately if youdevelop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite,yellow skin or eyes, or dark urine menominee termination acto. These symptoms may be early signs of liverproblems menominee termination acto.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption menominee termination acto. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea menominee termination acto. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar menominee termination acto.
• Store Actos at room temperature away from moisture and heat menominee termination acto.


What happens if I miss a dose?
• Take the missed dose as soon as you remember menominee termination acto. If you do not rememberuntil the next day, skip the missed dose and take only the next regularly scheduleddose menominee termination acto. Do not take a double dose menominee termination acto.


What happens if I overdose?
• Seek emergency medical attention menominee termination acto.
• Symptoms of a Actos overdose are not known menominee termination acto.


What should I avoid while taking Actos?
• Follow any diet, medication, and exercise routines closely menominee termination acto. Changingany of these factors can affect blood sugar levels menominee termination acto.
• Avoid alcohol menominee termination acto. It lowers blood sugar and may interfere with diabetestreatment menominee termination acto.
• Tell your doctor and dentist that you are taking this medication beforehaving surgery menominee termination acto.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor menominee termination acto.


What are the possible side effects of Actos?
• If you experience any of the following serious side effects, stop takingActos and seek emergency medical attention or notify your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· nausea, vomiting, abdominal pain, or loss of appetite;
· unusual fatigue;
· yellowing of the skin or eyes; or
· dark urine menominee termination acto.
• Notify your doctor immediately if you experience an unusually rapid increasein weight or edema (swelling, water retention), shortness of breath, or chestpain during treatment with Actos menominee termination acto. These may be early symptoms of heart problems menominee termination acto.
• Although Actos does not usually cause hypoglycemia (low blood sugar),hypoglycemia may result from skipped meals, excessive exercise, or alcohol consumption menominee termination acto. Know the signs and symptoms of hypoglycemia, which include headache, drowsiness,weakness, dizziness, fast heartbeat, sweating, tremor, and nausea menominee termination acto. Carry a pieceof hard candy or glucose tablets with you to treat episodes of low blood sugar menominee termination acto.
• Other less serious side effects may also occur menominee termination acto. Continue to take Actosand talk to your doctor if you experience:
· headache;
· muscle aches; or
· sore throat, nasal discharge, or cold symptoms menominee termination acto.
• Side effects other than those listed here may also occur menominee termination acto. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome menominee termination acto.


What other drugs will affect Actos?
• Actos may decrease the effects of some birth control pills menominee termination acto. Additionalmeasures may be necessary to prevent pregnancy while taking Actos menominee termination acto. Talk to yourdoctor about the use of birth control menominee termination acto.
• Before taking Actos, tell your doctor if you are taking ketoconazole(Nizoral) menominee termination acto. Ketoconazole may interact with Actos menominee termination acto.
• Do not take over-the-counter or prescription cough, cold, allergy, pain,or weight-loss medications during treatment with Actos without first talkingto your doctor menominee termination acto.
• Drugs other than those listed here may also interact with Actos or affectyour condition menominee termination acto. Talk to your doctor and pharmacist before taking any prescriptionor over-the-counter medicines, including herbal products menominee termination acto.


Where can I get more information?
• Your pharmacist has additional information about Actos written for healthprofessionals that you may read menominee termination acto.


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