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difference between trimipramine and amitriptyline
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difference between trimipramine and amitriptyline
(a mee TRIP ti leen)
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What is the most important information I should know about amitriptyline?
• It may be 4 weeks or more before you start to feel better, but do notstop taking amitriptyline without first talking to your doctor difference between trimipramine and amitriptyline.
• Use caution when driving, operating machinery, or performing other hazardousactivities difference between trimipramine and amitriptyline. Amitriptyline may cause drowsiness or dizziness difference between trimipramine and amitriptyline. If you experiencedrowsiness or dizziness, avoid these activities difference between trimipramine and amitriptyline.
• Dizziness is likely to occur when you rise from a sitting or lying position difference between trimipramine and amitriptyline. Rise slowly to prevent dizziness and a possible fall difference between trimipramine and amitriptyline.
• Use alcohol cautiously difference between trimipramine and amitriptyline. Alcohol may increase drowsiness and dizzinesswhile you are taking amitriptyline difference between trimipramine and amitriptyline.


What is amitriptyline?
• Amitriptyline is in a class of drugs called tricyclic antidepressants difference between trimipramine and amitriptyline. Amitriptyline affects chemicals in the brain that may become unbalanced andcause depression difference between trimipramine and amitriptyline.
• Amitriptyline is used to relieve symptoms of depression such as feelingsof sadness, worthlessness, or guilt; loss of interest in daily activities; changesin appetite; tiredness; sleeping too much; insomnia; and thoughts of death orsuicide difference between trimipramine and amitriptyline. Amitriptyline is also sometimes used to treat certain types of pain difference between trimipramine and amitriptyline.
• Amitriptyline may also be used for purposes other than those listed inthis medication guide difference between trimipramine and amitriptyline.


What should I discuss with my healthcare provider before taking amitriptyline?
• Do not take amitriptyline if you have taken a monoamine oxidase inhibitorsuch as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate)within the last 14 days difference between trimipramine and amitriptyline.
• Before taking amitriptyline, tell your doctor if you have
· liver disease;
· kidney disease;
· asthma;
· thyroid disease;
· diabetes;
· stomach or intestinal problems;
· high blood pressure or heart disease;
· had a heart attack in the last 6 weeks;
· an enlarged prostate or difficulty urinating; or
· glaucoma difference between trimipramine and amitriptyline.
• You may not be able to take amitriptyline, or you may require a dosageadjustment or special monitoring during treatment if you have any of the conditionslisted above difference between trimipramine and amitriptyline.
• Amitriptyline may be harmful to an unborn baby difference between trimipramine and amitriptyline. Do not take amitriptylinewithout first talking to your doctor if you are pregnant or could become pregnantduring treatment difference between trimipramine and amitriptyline.
• Amitriptyline passes into breast milk and may affect a nursing baby difference between trimipramine and amitriptyline. Do not take amitriptyline without first talking to your doctor if you are breast-feedinga baby difference between trimipramine and amitriptyline.
• If you are over 60 years of age, you may be more likely to experienceside effects such as drowsiness, dizziness, unsteadiness, feeling uncoordinated,and low blood pressure difference between trimipramine and amitriptyline. Your doctor may prescribe a lower dose of this medication difference between trimipramine and amitriptyline.


How should I take amitriptyline?
• Take amitriptyline exactly as directed by your doctor difference between trimipramine and amitriptyline. If you do notunderstand these directions, ask your pharmacist, nurse, or doctor to explainthem to you difference between trimipramine and amitriptyline.
• Take each dose with a full glass (8 oz) of water difference between trimipramine and amitriptyline.
• Amitriptyline may be taken several times a day or in one daily dose (usuallyat bedtime) difference between trimipramine and amitriptyline. Follow your doctor's instructions difference between trimipramine and amitriptyline.
• Do not stop taking amitriptyline suddenly difference between trimipramine and amitriptyline. This could cause symptomssuch as nausea, headache, and malaise difference between trimipramine and amitriptyline.
• It may be 4 weeks or more before you start to feel better, but do notstop taking amitriptyline without first talking to your doctor difference between trimipramine and amitriptyline.
• Store amitriptyline at room temperature away from moisture and heat difference between trimipramine and amitriptyline.


What happens if I miss a dose?
• Take the missed dose as soon as you remember difference between trimipramine and amitriptyline. If it is almost time forthe next regularly scheduled dose, skip the missed dose and take the next oneas directed difference between trimipramine and amitriptyline. Do not take a double dose of this medication unless otherwise directedby your doctor difference between trimipramine and amitriptyline.


What happens if I overdose?
• Seek emergency medical attention difference between trimipramine and amitriptyline.
• Symptoms of an amitriptyline overdose include seizures, confusion, drowsiness,agitation, hallucinations, and low blood pressure (dizziness, fatigue, fainting) difference between trimipramine and amitriptyline.


What should I avoid while taking amitriptyline?
• Use caution when driving, operating machinery, or performing other hazardousactivities difference between trimipramine and amitriptyline. Amitriptyline may cause drowsiness or dizziness difference between trimipramine and amitriptyline. If you experiencedrowsiness or dizziness, avoid these activities difference between trimipramine and amitriptyline.
• Dizziness is likely to occur when you rise from a sitting or lying position difference between trimipramine and amitriptyline. Rise slowly to prevent dizziness and a possible fall difference between trimipramine and amitriptyline.
• Use alcohol cautiously difference between trimipramine and amitriptyline. Alcohol may increase drowsiness and dizzinesswhile you are taking amitriptyline difference between trimipramine and amitriptyline.
• Do not stop taking amitriptyline suddenly difference between trimipramine and amitriptyline. This could cause symptomssuch as nausea, headache, and malaise difference between trimipramine and amitriptyline.


What are the possible side effects of amitriptyline?
• If you experience any of the following serious side effects, stop takingamitriptyline and contact your doctor immediately or seek emergency medicaltreatment:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, face, or tongue; or hives);
· seizures;
· a fast or irregular heartbeat;
· a heart attack;
· high blood pressure (blurred vision, headache);
· difficulty urinating; or
· fever with increased sweating, muscle stiffness, or severe muscle weakness difference between trimipramine and amitriptyline.
• Other, less serious side effects may be more likely to occur difference between trimipramine and amitriptyline. Continueto take amitriptyline and talk to your doctor if you experience
· drowsiness or dizziness;
· dry mouth and eyes;
· constipation;
· mild tremor;
· sweating;
· mild agitation, weakness, or headache;
· ringing in the ears;
· nausea; or
· loss of weight or appetite difference between trimipramine and amitriptyline.
• Side effects other than those listed here may also occur difference between trimipramine and amitriptyline. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome difference between trimipramine and amitriptyline.


What other drugs will affect amitriptyline?
• Do not take amitriptyline if you have taken a monoamine oxidase inhibitorsuch as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate)within the last 14 days difference between trimipramine and amitriptyline.
• Amitriptyline may increase the effects of other drugs that cause drowsiness,including other antidepressants, alcohol, antihistamines, sedatives (used totreat insomnia), pain relievers, anxiety medicines, and muscle relaxants difference between trimipramine and amitriptyline. Tellyour doctor about all medicines that you are taking, and do not take any otherprescription or over-the-counter medicines without first talking to your doctor difference between trimipramine and amitriptyline.
• Drugs other than those listed here may also interact with amitriptyline difference between trimipramine and amitriptyline. Talk to your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products difference between trimipramine and amitriptyline.


Where can I get more information?
• Your pharmacist has additional information about amitriptyline writtenfor health professionals that you may read difference between trimipramine and amitriptyline.

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