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What is the most important information I should know about Avelox?
• Take all of the Avelox that has been prescribed for you even if you beginto feel better avelox promotional. Your symptoms may start to improve before the infection is completelytreated avelox promotional.
• Do not take Avelox without first talking to your doctor if you or anymember of your family have a heart condition known as prolongation of the QTinterval avelox promotional. Also, do not take Avelox if you are being treated for heart rhythmdisturbances with drugs such as quinidine (Cardioquin, Quinidex, Quinaglute,others), procainamide (Pronestyl, Procan SR, others), amiodarone (Cordarone,Pacerone, others), sotalol (Betapace), and others avelox promotional.
• Take Avelox at least 4 hours before or 8 hours after antacids that containmagnesium, calcium, or aluminum (e.g., Tums, Rolaids, Maalox, others); the ulcermedicine sucralfate (Carafate); vitamin or mineral supplements that containiron or zinc; or didanosine chewable/buffered tablets or pediatric powder fororal solution (ddI, Videx, Videx Pediatric, others) avelox promotional. These medicines may decreasethe effectiveness of Avelox avelox promotional.
• Use caution when driving, operating machinery, or performing other hazardousactivities avelox promotional. Avelox may cause dizziness avelox promotional. If you experience dizziness, avoid theseactivities avelox promotional.


What is Avelox?
• Avelox is an antibiotic in the class of drugs called fluoroquinolones avelox promotional. It fights bacteria in the body avelox promotional.
• Avelox is used to treat bacterial infections including pneumonia, sinusitis,and worsening of chronic bronchitis avelox promotional.
• Avelox may also be used for purposes other than those listed in thismedication guide avelox promotional.


What should I discuss with my healthcare provider before taking Avelox?
• Do not take Avelox without first talking to your doctor if you or anymember of your family have a heart condition known as prolongation of the QTinterval avelox promotional. Also, do not take Avelox if you are being treated for heart rhythmdisturbances with drugs such as quinidine (Cardioquin, Quinidex, Quinaglute,others), procainamide (Pronestyl, Procan SR, others), amiodarone (Cordarone,Pacerone, others), sotalol (Betapace), and others avelox promotional.
• Before taking Avelox, tell your doctor if you have
· a low level of potassium in your blood;
· a slow heart rate;
· heart disease;
· liver disease; or
· epilepsy or another seizure disorder avelox promotional.
• You may not be able to take Avelox or you may require a dosage adjustmentor special monitoring during your treatment avelox promotional.
• Avelox is in the FDA pregnancy category C avelox promotional. This means that it is notknown whether Avelox will be harmful to an unborn baby avelox promotional. Do not take Avelox withoutfirst talking to your doctor if you are pregnant or could become pregnant duringtreatment avelox promotional.
• It is unknown whether Avelox passes into breast milk avelox promotional. Do not take Aveloxwithout first talking to your doctor if you are breast feeding a baby avelox promotional.
• Avelox is not approved for use by children younger than 18 years old avelox promotional.


How should I take Avelox?
• Take Avelox exactly as directed by your doctor avelox promotional. If you do not understandthese instructions, ask your pharmacist, nurse, or doctor to explain them toyou avelox promotional.
• Take each oral dose with a full glass (8 ounces) of water avelox promotional. Drink plentyof fluid while taking Avelox avelox promotional.
• Avelox can be taken with or without food avelox promotional.
• Avelox is usually taken once a day avelox promotional. Take each dose at the same time everyday avelox promotional. Follow your doctor's instructions avelox promotional.
• Avelox may also be given by a healthcare provider by intravenous (IV)infusion avelox promotional.
• Take all of the Avelox that has been prescribed for you even if you beginto feel better avelox promotional. Your symptoms may start to improve before the infection is completelytreated avelox promotional.
• Take Avelox at least 4 hours before or 8 hours after antacids that containmagnesium, calcium, or aluminum (e.g., Tums, Rolaids, Maalox, others); the ulcermedicine sucralfate (Carafate); vitamin or mineral supplements that containiron or zinc; or didanosine chewable/buffered tablets or pediatric powder fororal solution (ddI, Videx, Videx Pediatric, others) avelox promotional. These medicines may decreasethe effectiveness of Avelox avelox promotional.
• Store this medication at room temperature away from moisture and heat avelox promotional.


What happens if I miss a dose?
• Take the missed dose as soon as you remember avelox promotional. However, if it is almosttime for the next dose, skip the missed dose and take only the next regularlyscheduled dose avelox promotional. Do not take a double dose of this medication avelox promotional.


What happens if I overdose?
• Seek emergency medical attention avelox promotional.
• Symptoms of a Avelox overdose include seizures, poor coordination, tremors,sleepiness, vomiting and diarrhea avelox promotional.


What should I avoid while taking Avelox?
• Avoid prolonged exposure to sunlight avelox promotional. Although it has not been reportedwith the use of Avelox, other similar medicines have caused increased sensitivityof the skin to sunlight avelox promotional. Severe sunburn has resulted, even with minimal sunexposure avelox promotional. If exposure to the sun is unavoidable while taking Avelox, wear protectiveclothing and use sunscreen avelox promotional. Call your doctor if you experience severe burning,redness, itching, rash, or swelling after exposure to the sun avelox promotional.
• Use caution when driving, operating machinery, or performing other hazardousactivities avelox promotional. Avelox may cause dizziness avelox promotional. If you experience dizziness, avoid theseactivities avelox promotional.


What are the possible side effects of Avelox?
• If you experience any of the following serious side effects, stop takingAvelox and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· irregular or rapid heartbeats;
· fainting;
· seizures;
· liver damage (yellowing of the skin or eyes, nausea, abdominal painor discomfort, unusual bleeding or bruising, severe fatigue);
· muscle or joint pain; or
· skin rash avelox promotional.
• If you experience any of the following less serious side effects, continuetaking Avelox and talk to your doctor:
· nausea, vomiting, abdominal pain, or diarrhea;
· dizziness;
· headache; or
· increased sensitivity of the skin to sunlight avelox promotional.
• Side effects other than those listed here may also occur avelox promotional. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome avelox promotional.


What other drugs will affect Avelox?
• Take Avelox at least 4 hours before or 8 hours after antacids that containmagnesium, calcium, or aluminum (e.g., Tums, Rolaids, Maalox, others); the ulcermedicine sucralfate (Carafate); vitamin or mineral supplements that containiron or zinc; or didanosine chewable/buffered tablets or pediatric powder fororal solution (ddI, Videx, Videx Pediatric, others) avelox promotional. These medicines may decreasethe effectiveness of Avelox avelox promotional.
• Do not take Avelox without first talking to your doctor if you are takingany of the following drugs:
· the heart medicines quinidine (Cardioquin, Quinidex, Quinaglute, others),procainamide (Pronestyl, Procan SR, others), amiodarone (Cordarone, Pacerone,others), sotalol (Betapace), and others;
· a tricyclic antidepressant including amitriptyline (Elavil, Endep),amoxapine (Asendin), imipramine (Tofranil), nortriptyline (Pamelor), doxepin(Sinequan), and others;
· a phenothiazine including chlorpromazine (Thorazine), fluphenazine(Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril),and others;
· erythromycin (E-Mycin, Ery-Tab, E.E.S., others); or
· cisapride (Propulsid) avelox promotional.
• Avelox and the drugs listed above may affect the rhythm of your heartbeats avelox promotional. You may not be able to take Avelox, or you may require a dosage adjustment orspecial monitoring during treatment if you are taking any of the medicines listedabove avelox promotional.
• Before taking Avelox, tell your doctor if you are taking:
· warfarin (Coumadin); or
· a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,Advil, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (OrudisKT, Orudis, Oruvail), and others avelox promotional.
• You may not be able to take Avelox, or you may require a dosage adjustmentor special monitoring during treatment if you are taking any of the medicineslisted above avelox promotional.
• Drugs other than those listed here may also interact with Avelox avelox promotional. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products avelox promotional.


Where can I get more information?
• Your pharmacist has additional information about Avelox written for healthprofessionals that you may read avelox promotional.


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